SBNO2 Antibody, FITC conjugated - Cat. #: CSB-PA896873LC01HU

SKU: CSB-PA896873LC01HU

Size :50ug

Clone Number:

Aliases:SBNO2 antibody; KIAA0963Protein strawberry notch homolog 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y2G9

Immunogen:Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages (PubMed:18025162). Plays a role as a regulator in the proinflammatory cascade (PubMed:18025162).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SBNO2

Research Areas:Epigenetics and Nuclear Signaling; Immunology