SBDS Antibody, Biotin conjugated - Cat. #: CSB-PA897481LD01HU

SKU: CSB-PA897481LD01HU

Size :50ug

Clone Number:

Aliases:4733401P19Rik antibody; AI836084 antibody; CGI 97 antibody; CGI-97 antibody; FLJ10917 antibody; MGC105922 antibody; Protein 22A3 antibody; Ribosome maturation protein SBDS antibody; sbds antibody; SBDS_HUMAN antibody; SDS antibody; Shwachman Bodian Diamond syndrome protein antibody; Shwachman Bodian Diamond syndrome protein homolog antibody; Shwachman Bodian-Diamond syndrome antibody; Shwachman-Bodian-Diamond syndrome protein antibody; SWDS antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y3A5

Immunogen:Recombinant Human Ribosome maturation protein SBDS protein (37-153AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SBDS

Research Areas:Epigenetics and Nuclear Signaling