SAFB antibody , Cat. # FNab07578

SKU: FNab07578

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Binds to scaffold/matrix attachment region(S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex(consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing(By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter(By similarity). Can inhibit cell proliferation.

Immunogen:scaffold attachment factor B

Synonyms:HAP, HET, SAFB1

Observed MW:150 kDa

Uniprot ID:Q15424

Reactivity:Human

Tested Application:ELISA, WB, IF, IHC

Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID:6294

Research Area:Metabolism