RUNX2 Polyclonal Antibody

SKU: E-AB-30103

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: RUNX2

Target Synonym: Acute myeloid leukemia 3 protein;Alpha subunit 1;AML3;CBF alpha 1;CBF-alpha-1;CBFA1;CCD;CCD1;Cleidocranial dysplasia 1;Core binding factor;Core binding factor runt domain alpha subunit 1;Core binding factor subunit alpha 1;Core-binding factor subunit alpha-1;MGC120022;MGC120023;Oncogene AML 3;Oncogene AML-3;OSF 2;OSF-2;OSF2;Osteoblast specific transcription factor 2;Osteoblast-specific transcription factor 2;OTTHUMP00000016533;PEA2 alpha A;PEA2-alpha A;PEA2aA;PEBP2 alpha A;PEBP2-alpha A;PEBP2A1;PEBP2A2;PEBP2aA;PEBP2aA1;Polyomavirus enhancer binding protein 2 alpha A subunit;Polyomavirus enhancer-binding protein 2 alpha A subunit;Runt domain;Runt related transcription factor 2;Runt-related transcription factor 2;RUNX2;RUNX2;SL3 3 enhancer factor 1 alpha A subunit;SL3-3 enhancer factor 1 alpha A subunit;SL3/AKV core binding factor alpha A subunit;SL3/AKV core-binding factor alpha A subunit

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Developmental Biology;Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q13950

Accession:

Background: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity). Inhibits MYST4-dependent transcriptional activation.

Concentration: 1mg/mL

Immunogen: Synthesized peptide derived from the Internal region of human RUNX2.

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IF 1:50-1:200

Calculated MW: 57kDa

ObservedMW: 56kDa