RPS6KB1 Monoclonal Antibody

SKU: BT-MCA3615

Size:100μL

Background:This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.

Research_area:Cell Biology

Target_protein:RPS6KB1

applications:IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5G9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:RPS6KB1

Immunogen:Purified recombinant fragment of human RPS6KB1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):59kDa

UniProt accession:P23443

Synonyms:S6K, PS6K, S6K1, STK14A, p70-S6K, p70-alpha, p70(S6K)-alpha

GeneID:6198