RPS3 Antibody - Cat. #: CSB-PA136884

SKU: CSB-PA136884

Size :100ul

Clone Number:

Aliases:40S ribosomal protein S3 antibody; fb13d09 antibody; FLJ26283 antibody; FLJ27450 antibody; IMR 90 ribosomal protein S3 antibody; MGC56088 antibody; MGC87870 antibody; OTTHUMP00000229804 antibody; OTTHUMP00000229805 antibody; OTTHUMP00000229874 antibody; OTTHUMP00000229877 antibody; OTTHUMP00000229878 antibody; OTTHUMP00000229879 antibody; OTTHUMP00000229880 antibody; OTTHUMP00000229882 antibody; OTTHUMP00000229883 antibody; OTTHUMP00000229886 antibody; Ribosomal protein S3 antibody; rps3 antibody; RS3_HUMAN antibody; S3 antibody; wu:fb13d09 antibody; zgc:56088 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P23396

Immunogen:Synthesized peptide derived from internal of Human RPS3.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Yoshihama M., Genome Res. 12:379-390(2002).
Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).
Molina H., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RPS3

Research Areas:Epigenetics and Nuclear Signaling;Cell biology