RNF20 Antibody - Cat. #: CSB-PA942697

SKU: CSB-PA942697

Size :50ul

Clone Number:

Aliases:BRE1 A antibody; BRE1 antibody; BRE1 E3 ubiquitin ligase homolog antibody; BRE1-A antibody; BRE1A antibody; BRE1A_HUMAN antibody; E3 ubiquitin-protein ligase BRE1A antibody; hBRE1 antibody; Homolog of S. cerevisiae BRE1 antibody; RING finger protein 20 antibody; Ring finger protein 20 E3 ubiquitin protein ligase antibody; Rnf20 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q5VTR2

Immunogen:Fusion protein of Human RNF20

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:10-1:50

Background:The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RNF20

Research Areas:Cell biology