REPS1 (phospho-Ser709) rabbit pAb

SKU: ES13425

Size: 100μL

Source:Rabbit

Applications:WB;IHC

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000;IHC-p 1:50-300

Immunogen:Synthesized phosho peptide around human REPS1 (Ser709)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):80kD

Human_gene_id:85021

Human_swiss_prot_no:Q96D71

Subcellular_location:Membrane, clathrin-coated pit . Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits.

Other_name:RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1)

Background:This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],