Recombinant VEGFA Monoclonal Antibody

SKU: AN300844L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:VEGFA

Target Synonym:MVCD;Vascular Endothelial Growth Factor Isoform;VEGFA;MVCD1;VEGF;VPF;L VEGFA;VEGF A;Folliculostellate cell-derived growth factor;Glioma-derived endothelial cell mitogen;Vascular Endothelial Growth Factor Isoform 165;Vascular permeability factor;VEGF121;VEGF165;VEGF-165;VEGF-A;Vascular endothelial growth factor A;Vascular permeability factor (VPF);MVCD1;vascular endothelial growth factor A;VEGF;VPF;MGC70609;vascular endothelial growth factor;vascular endothelial growth factor A121;vascular endothelial growth factor A165;VEGF120;VEGF-A

Research Areas:Cardiovascular;Signal Transduction;Cancer;Developmental Biology;Kits;Lysates;Other;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5H3

UNIProt ID:P15692

Accession:

Background:This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human VEGFA protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:1000-1:5000;WB 1:2000-1:10000

Calculated MW:27 kDa

ObservedMW:40 kDa