Recombinant UQCRFS1/RISP Monoclonal Antibody

SKU: AN301884L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:UQCRFS1/RISP

Target Synonym:RIS;RIP;UQCR;UQCRFS;UQCRFS1;RIP1;RIS1;RISP;UQCR5

Research Areas:Microbiology;Signal Transduction;Cell Biology;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A596

UNIProt ID:P47985

Accession:

Background:Ubiquinol-cytochrome c reductase iron-sulfur subunit (UQCRFS1), also known as Rieske iron-sulfur protein (RISP), is a component of Complex III in the mitochondrial electron transport chain. UQCRFS1/RISP and two other subunits, cytochrome b (MT-CYB) and cytochrome c1 (CYC1), are essential for the catalytic activity of Complex III. Studies show that UQCRFS1/RISP is required for fetal mouse hematopoietic stem cell differentiation and adult mouse hematopoietic stem cell quiescence. In addition, loss of UQCRFS1/RISP decreases the strength of T cell receptor (TCR) signaling, indicating that this protein is critical for optimal TCR signaling.

Concentration:1 mg/mL

Immunogen:Recombinant human UQCRFS1/RISP fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:5000;IHC 1:200-1:1000;IP 1:50-1:100

Calculated MW:30 kDa

ObservedMW:25 kDa