Recombinant SARS-CoV-2 3C-like Proteinase Protein (His Tag)

SKU: PKSR030465

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Viral Proteins

Abbreviation: 3C-likease

Target Synonym: 3CL Proteinase;M Proteinase

Research Areas:

Conjugation:

Target Species: SARS-CoV-2

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID:

Accession: P0DTC1

Background: The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

Concentration:

Activity: Not validated for activity

Sequence: Ser3264-Gln3569

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μM filtered solution of PBS, 1 mM EDTA, 10% Glycerol, pH 7.4.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 36.1 kDa

ObservedMW: 33 kDa