Recombinant Rat CINC-2 Beta/CXCL3 protein

SKU: CD00135

Size:2 ug

Background:CXCL3 is belonging to the CXC chemokine family, which is also known as CINC-2 in rat, DCIP-1 in Mouse, and GROγ in humans. The functional receptor for CXCL3 has been identified as CXCR2. Similar to other GRO proteins, CXCL3 is potent neutrophil attractants and activators. This chemokine were originally purified from the conditioned medium of rat granulation tissue. In rat, CINC-2 has two isoforms, known as CXCL3α/CINC-2α and CXCL3β/CINC-2β. CXCL3α differs from CXCL3β as DKSS to PSL (98-101) at carboxy-terminal residues.

Research_area:Immunology

Purity:> 96 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Rat Cytokine-induced Neutrophil Chemoattractant-2 beta/CXCL3

Biological activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected Mouse BaF3 cells is in a concentration range of 5-5 ng/ml.

Synonyms:CINC-2β/CXCL3,Cinc2; Cinc-2; Gm196, Rat

Endotoxin:Less than 1 EU/μg of rRtCINC-2β/CXCL3 as determined by LAL method.

Storage:-20ºC

Sequence:RELRCQCLKT LPRVDFENIQ SLTVTPPGPH CTQTEVIATL KDGQEVCLNP QAPRLQKIIQ KLLKSPSL

uniprot accession:Q1746

Molecular weight:Approximately 7.6 kDa, a single non-glycosylated polypeptide chain containing 68 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2 mM PB, pH 7.4, 5 mM NaCl.