Recombinant PUMA Monoclonal Antibody

SKU: AN300815L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:PUMA

Target Synonym:BBC;PUMA;BBC3;BBC 3;BBC3_HUMAN;BCL 2 binding component 3;BCL2 binding component 3;Bcl-2-binding component 3;JFY 1;JFY1;JFY-1;p53 up regulated modulator of apoptosis;p53 Upregulated Modulator of Apoptosis;p53 up-regulated modulator of apoptosis;PUMA alpha;PUMA/JFY1

Research Areas:Cell Biology;Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:4B14

UNIProt ID:Q9BXH1

Accession:

Background:This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human PUMA protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:21 kDa

ObservedMW:21 kDa