Recombinant Phospho-Tau (S262) Monoclonal Antibody

SKU: AN301700L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies;Acetyl/Phospho/Methyl Antibodies

Abbreviation:Phospho-Tau (S262)

Target Synonym:FTDP;PPP1R;DDPAC;FTDP-17;MAPTL;MSTD;MTBT1;MTBT2;PPND;PPP1R103;TAU;MAPT;Microtubule-Associated Protein Tau;Neurofibrillary Tangle Protein;Paired Helical Filament-Tau;PHF-Tau;pMAPT/pTAU;TAU and MAPT;N/A;AI413597;AW045860;FLJ31424;FTDP 17;G protein beta1/gamma2 subunit interacting factor 1;included;MGC134287;MGC138549;MGC156663;Microtubule associated protein tau;Microtubule associated protein tau isoform 4;Mtapt;Paired helical filament tau;PHF tau;Protein phosphatase 1;pTau;regulatory subunit 103;RNPTAU;Tauopathy and respiratory failure

Research Areas:Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A408

UNIProt ID:P10636

Accession:

Background:Tau is a neuronal microtubule-associated protein, which is mainly located in the cytoplasm, cytoskeleton and cell membrane. Tau is expressed in neuronal tissues and exists in the form of a variety of alternate splicing subtypes. Its C-terminus is combined with axon microtubules, and the N-terminus is combined with neuroplasmic membrane components to maintain the stability and plasticity of the neuronal cytoskeleton. In neurons, hyperphosphorylated and abnormally glycosylated Tau protein accumulates, causing neurofibrosis and neurodegeneration, such as Alzheimer’s disease (AD), frontotemporal dementia, and chronic traumatic encephalopathy (CTE), Parkinson's disease after encephalitis, etc.

Concentration:1 mg/mL

Immunogen:Recombinant human Tau (phospho S262) fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000

Calculated MW:79 kDa

ObservedMW:50 kDa