Recombinant Phospho-PTP1B (Ser386) Monoclonal Antibody

SKU: AN301643L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies;Acetyl/Phospho/Methyl Antibodies

Abbreviation:Phospho-PTP1B (Ser386)

Target Synonym:PTPN;PTPN1;PTP1B

Research Areas:Signal Transduction;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IF

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A346

UNIProt ID:P18031

Accession:

Background:Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.

Concentration:1 mg/mL

Immunogen:Recombinant human Phospho-PTP1B (Ser386) fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IF 1:50

Calculated MW:50 kDa

ObservedMW:50 kDa