Recombinant Phospho-p70 S6 Kinase (Thr389) Monoclonal Antibody

SKU: AN301393L

Size::

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:p70 S6 Kinase

Target Synonym:RPS6KB;S6K-beta;PS6K;S6K;S6K-beta-1;S6K1;STK14A;p70 S6KA;p70(S6K)-alpha;p70-S6K;p70-alpha;P70 S6K;RPS6KB1;p70S6KA;70 kDa ribosomal protein S6 kinase 1;alpha 1;alpha 2;KS6B1;p70 alpha;P70 beta 1;p70 ribosomal S6 kinase alpha;p70 ribosomal S6 kinase beta 1;P70 S6 Kinase;p70 S6 kinase alpha;p70 S6K-alpha;p70(S6K) alpha;P70S6K;p70-S6K 1;P70S6K1;p70S6Kb;Ribosomal protein S6 kinase 70kDa polypeptide 1;Ribosomal protein S6 kinase beta 1;Ribosomal protein S6 kinase beta-1;Ribosomal protein S6 kinase I;Serine/threonine kinase 14 alpha;Serine/threonine-protein kinase 14A;p70 S6 kinase α

Research Areas:Cell Biology;Epigenetics and Nuclear Signaling;Signal Transduction;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11A4

UNIProt ID:P23443

Accession:

Background:RPS6KB1(ribosomal protein S6 kinase B1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Concentration:0.2 mg/mL

Immunogen:A synthetic peptide corresponding to residues around (Thr389) of Human Phospho-p70 S6 Kinase

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:59 kDa

ObservedMW:70 kDa