Recombinant PDGFR-β Monoclonal Antibody

SKU: AN300813L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:PDGFR-β

Target Synonym:IMF;JTK;IBGC;CD140B;IBGC4;IMF1;JTK12;KOGS;PDGFR;PDGFR-1;PDGFR1;PENTT;PDGF Receptor beta;PDGFRB;PDGFR beta;PDGF-RβBeta platelet derived growth factor receptor;Beta Platelet-Derived Growth Factor Receptor;Beta-type platelet-derived growth factor receptor;CD 140B;CD140 antigen-like family member B;CD140b antigen;OTTHUMP00000160528;PDGF R beta;PDGFR 1;PDGFR-Beta;PDGF-R-beta;PGFRB;Platelet derived growth factor receptor 1;platelet derived growth factor receptor beta;Platelet derived growth factor receptor beta polypeptide;Platelet-Derived Growth Factor Receptor 1;Platelet-Derived Growth Factor Receptor Beta

Research Areas:Cardiovascular;Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:4B12

UNIProt ID:P09619

Accession:

Background:This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human PDGFR-β protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:124 kDa

ObservedMW:190 kDa