Recombinant NRAS Monoclonal Antibody

SKU: AN300969L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:NRAS

Target Synonym:ALPS;HRAS;NRAS;ALPS4;CMNS;N-ras;NCMS;NRAS1;NS6;GTPase NRas;GTPase;HRAS1;RASN;Transforming protein N-Ras;AV095280;N ras;N ras protein part 4;Neuroblastoma RAS viral (v ras) oncogene homolog;OTTHUMP00000013879;OTTMUSP00000023521;Transforming protein N Ras;v ras neuroblastoma RAS viral oncogene homolog;N-RAS

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling;Cancer;Tags & Cell Markers

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:10A3

UNIProt ID:P01111

Accession:

Background:This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human NRAS protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000

Calculated MW:22 kDa

ObservedMW:22 kDa