Recombinant NF2 Monoclonal Antibody

SKU: AN301159L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:NF2

Target Synonym:Neurofibromin;Neurofibromatosis type;NF2;ACN;BANF;SCH;merlin;Bilateral acoustic neuroma;CAN;MERL_HUMAN;Moesin ezrin radixin like protein;Moesin ezrin radizin like;Moesin-ezrin-radixin-like;Neurofibromatosis 2;Neurofibromatosis type 2;Neurofibromatosis2;NF 2;Schwannomerlin;Schwannomin;Neurofibromin 2;neurofibromin 2 (merlin);NF2

Research Areas:Neuroscience;Signal Transduction;Epigenetics and Nuclear Signaling;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11G8

UNIProt ID:P35240

Accession:

Background:This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human NF2 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:70 kDa

ObservedMW:70 kDa