Recombinant Neurofilament (NF-L) Monoclonal Antibody

SKU: AN301288L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Neurofilament

Target Synonym:PPP1R;NEFL;CMT1F;CMT2E;NF-L;NF68;NFL;PPP1R110;68 kDa neurofilament protein;CMTDIG;light polypeptide;neurofilament;neurofilament light;FLJ53642;Neurofilament Light Polypeptide;Neurofilament triplet L protein;68kDa Neurofilament;68kDa Neurofilament;CMT1F;CMT2E;FLJ53642;Neurofilament Light Polypeptide;Neurofilament triplet L protein;NFL;NF-L;NF-L

Research Areas:Neuroscience;Signal Transduction;Stem Cells;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:4D5

UNIProt ID:P07196

Accession:

Background:Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Neurofilament (NF-L) protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:2000-1:10000

Calculated MW:

ObservedMW: