Recombinant Nampt Monoclonal Antibody

SKU: E-AB-81515

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:Nampt

Target Synonym:1110035O14Rik;AI314458;AI480535;DKFZP666B131;EC 2.4.2.12;MGC117256;NAmPRTase;Nampt;NAMPT;Nicotinamide phosphoribosyltransferase;PBEF 1;PBEF;PBEF1;Pre B cell colony enhancing factor 1;Pre B cell colony enhancing factor;Pre B cell enhancing factor;Pre-B cell-enhancing factor;Pre-B-cell colony-enhancing factor 1;VF;Visfatin

Research Areas:Cancer;Cardiovascular;Metabolism;Immunology;Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC-P

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:R05-4C4

UNIProt ID:P43490

Accession:

Background:Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide,an intermediate in the biosynthesis of NAD,which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow,liver tissue,and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus (T2DM),and it is now evidenced that NAMPT may plays a role in lipid metabolism.

Concentration:300 μg/mL

Immunogen:A synthetic peptide of human Visfatin

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification method:Affinity Purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100

Calculated MW:56kDa

ObservedMW:56kDa