Recombinant Mouse Interleukin-2/IL-2 Protein (active)

SKU: PKSM041523

Size:50μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:Interleukin-2/IL-2

Target Synonym:Interleukin-2;IL-2;T-Cell Growth Factor;TCGF;Aldesleukin

Research Areas:Immunology

Conjugation:

Target Species:Mouse

Expression Host:HEK293 cells

Application:

Fusion tag:C-His

UNIProt ID:P04351

Accession:P04351

Background:Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes.

Concentration:

Activity:Measured in a cell proliferation assay using HT-2 mouse T cells. The ED50 for this effect is 0.88-3.5 ng/mL, corresponding to a specific activity of 2.86×105-1.14×106 units/mg.

Sequence:Ala21-Gln169

Purity:> 95 % as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Reconstitution:Please refer to the printed manual for detailed information.

Endotoxin:≤0.1 EU per μg by the LAL method.

Calculated MW:18.07 kDa

ObservedMW:22-25 kDa