Recombinant Mouse DCIP-1/CXCL3 protein

SKU: CD00488

Size:2 ug

Background:CXCL3, also known as DCIP1 in Mouse, CINC2 in rat, and GROγ in humans, is belonging to the CXC chemokine family. It is encoded by the gene CXCL3 in mouse. The functional receptor for CXCL3 has been identified as CXCR2. Similar to other GRO proteins, CXCL3 is potent neutrophil attractants and activators. CXCL3 plays a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. The amino acid sequence of Mouse CXCL3 is 57 % identical to human CXCL3.

Research_area:Immunology

Purity:> 97 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Mouse Dendritic Cell Inflammatory Protein-1/CXCL3

Biological activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 1-1 ng/ml.

Synonyms:DCIP-1/CXCL3, Dci; Dcip1; Gm196,Mouse

Endotoxin:Less than 1 EU/μg of rMuDCIP-1/CXCL3 as determined by LAL method.

Storage:-20ºC

Sequence:AVVASELRCQ CLNTLPRVDF ETIQSLTVTP PGPHCTQTEV IATLKDGQEV CLNPQGPRLQ IIIKKILKSG KSS

uniprot accession:Q6W5C

Molecular weight:Approximately 7.9 kDa, a single, non-glycosylated polypeptide chain containing 73 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in PBS, pH 7.4.