Recombinant Mouse Betacellulin protein

SKU: CD00612

Size:5 ug

Background:Betacellulin (BTC) encoded by the BTC gene located on the chromosome 4, is a member of the EGF family that also includes EGF, TGF-alpha, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. BTC is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum. Mouse BTC is expressed as a 178-amino acid precursor and the amino acid sequence of the mature form is 80 % identical with human BTC. Both human and mouse BTC exhibit significant overall similarity with other members of the EGF family. Recombinant Mouse Betacellulin is a heparin binding protein containing 80 amino acids residues.

Research_area:Immunology

Purity:> 96 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Mouse Betacellulin

Biological activity:Fully biologically active when compared to standard. The ED5 as determined by a cell proliferation assay using Mouse Balb/c 3T3 cells is less than .1 ng/ml, corresponding to a specific activity of > 1. × 18 IU/mg.

Synonyms:Betacellulin, BCN,BTC,Mouse

Endotoxin:Less than 1 EU/μg of rMuBetacellulin as determined by LAL method.

Storage:-20ºC

Sequence:DGNTTRTPET NGSLCGAPGE NCTGTTPRQK VKTHFSRCPK QYKHYCIHGR CRFVVDEQTP SCICEKGYFG ARCERVDLFY

uniprot accession: Q543J8

Molecular weight:Recombinant human Betacellulin is a 9. kDa monomeric protein, containing 8 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2 × PBS, pH 7.4.