Recombinant Mouse 78KDA glucose-regulated protein(Hspa5)

Recombinant Mouse 78KDA glucose-regulated protein(Hspa5)

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>Several Other Sizes Are Also Available. Please Inquire. Default Size: 200ug

Updated Date: Stock Protein updated on 20171228

Research areas: Tags & Cell Markers

Target / Protein: Hspa5

Biologically active: Not Tested

Expression system: Yeast

Species of origin: Mus musculus (Mouse)

Delivery time: 3-7 business days

Uniprot ID: P20029


Tag info: N-terminal 6xHis-tagged

Expression Region: 20-655aa

Protein length: Full Length of Mature Protein

MW: 72.5 kDa

Alternative Name(s): Short name: GRP-78 Alternative name(s): Heat shock 70KDA protein 5 Immunoglobulin heavy chain-binding protein Short name: BiP

Relevance: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate (By similarity).

Reference: "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.Mol. Cell 50:919-930(2013)

Purity: Greater than 90% as determined by SDS-PAGE.

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.