Recombinant LSD2/AOF1 Monoclonal Antibody

SKU: AN301732L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:LSD2/AOF1

Target Synonym:AOF;LSD;C6orf;AOF1;C6orf193;LSD2;KDM1B

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IF;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A440

UNIProt ID:Q8NB78

Accession:

Background:LSD2, also known as AOF1, is a Lysine (K)-specific demethylase that is encoded by the KDM1B gene in human. LSD2 demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD2 demethylates both mono- and Dimethylated 'Lys-4' of histone H3. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.

Concentration:1 mg/mL

Immunogen:Recombinant human LSD2/AOF1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:2000;IF 1:50;FCM 1:50-1:100

Calculated MW:92 kDa

ObservedMW:100 kDa