Recombinant IκB-α Monoclonal Antibody

SKU: AN300686L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:IκB-α

Target Synonym:EDAID;MAD;IKBA;MAD-3;NFKBI;IKB alpha;NFKBIA;EDAID2;I kappa B alpha;IkappaBalpha;I-kappa-B-alpha;IKBalpha;IkB-alpha;MAD 3;NF kappa B inhibitor alpha;MAD3;alpha;Major histocompatibility complex enhancer-binding protein MAD3;NF-kappa-B inhibitor alpha;Nuclear factor of kappa light chain gene enhancer in B cells;Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor;pIκBα

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling;Cancer;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6A7

UNIProt ID:P25963

Accession:

Background:This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human IκB-α protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:36 kDa

ObservedMW:36 kDa