Recombinant IGF2R/CI-M6PR Monoclonal Antibody

SKU: AN301859L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:IGF2R/CI-M6PR

Target Synonym:MPR;IGF2R;CD222;CI-M6PR;CIMPR;M6P-R;M6P/IGF2R;MPR 300;MPR1;MPR300;MPRI;cation-independent mannose-6-phosphate receptor;IGF-IIR;300 kDa mannose 6 phosphate receptor;300 kDa mannose 6-phosphate receptor;cation independent;Cation independent mannose 6 phosphate receptor;CD222 antigen;CI Man 6 P receptor;CI Man-6-P receptor;CI MPR;CI-MPR;IGF 2 receptor;IGF 2R;IGF II receptor;IGF2 receptor;IGF-II receptor;Insulin like growth factor 2 receptor;Insulin like growth factor II receptor;Insulin-like growth factor 2 receptor;Insulin-like growth factor II receptor;M6P R;M6P/IGF2 receptor;M6PR;mannose 6 phosphate receptor

Research Areas:Immunology;Tags & Cell Markers;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A571

UNIProt ID:P11717

Accession:

Background:The HAP1 is a nuclear enzyme that apparently performs two distinct roles in the cellular defense against oxidative stress. One well-established role is in the repair of a variety of lesions induced in DNA either by spontaneous hydrolysis or by reactive oxygen species (ROS). This function has been characterized in great detail and the roles played by individual active site amino acid residues have been defined. The second role, which was identified only relatively recently and is still not characterized in detail, is to regulate the DNA binding activity of a group of nuclear factors.

Concentration:1 mg/mL

Immunogen:Recombinant human IGF2R/CI-M6PR fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:200

Calculated MW:274 kDa

ObservedMW:300 kDa