Recombinant IGF1 Receptor Monoclonal Antibody

SKU: AN301096L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:IGF1 Receptor

Target Synonym:JTK;IGF1R;CD221;IGFIR;IGFR;JTK13;CD221 antigen;IGF-1R;IGF-I R;IGF-I receptor;IGF-IR;insulin-like growth factor 1 receptor;IGF-1R

Research Areas:Signal Transduction;Cancer;Developmental Biology;Neuroscience;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6A5

UNIProt ID:P08069

Accession:

Background:This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human IGF1 Receptor protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:100-200;WB 1:1000-5000

Calculated MW:154 kDa

ObservedMW:200 kDa