Recombinant Human TNFSF4/OX40L Protein (mFc Tag)

SKU: PKSH033572

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Immune Checkpoint Proteins

Abbreviation: TNFSF4;OX40L

Target Synonym: CD134L;CD252;GP34;Glycoprotein Gp34;OX-40;OX40 ligand;OX40L;TAX transcriptionally-activated glycoprotein 1;TNFSF4;TXGP1;Tumor necrosis factor ligand superfamily member 4

Research Areas: immunology;Stem cells

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-mFc

UNIProt ID: P23510

Accession: P23510

Background: Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed on the surface of activated B cells;T cells;dendritic cells and endothelial cells. OX40L binds to OX40(CD134);a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional;it has been found association with systemic lupus erythematosus;no association with occurrence of atherosclerosis.

Concentration:

Activity: Not validated for activity

Sequence: Gln51-Leu183

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 42.2 kDa

ObservedMW: 50-70 kDa