Recombinant Human TNFSF4/OX40L protein (His tag)

SKU: PDMH100152

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Immune Checkpoint Proteins

Abbreviation:TNFSF4;OX40L

Target Synonym:CD134L;CD252;GP34;Glycoprotein Gp34;OX-40;OX40 ligand;OX40L;TAX transcriptionally-activated glycoprotein 1;TNFSF4;TXGP1;Tumor necrosis factor ligand superfamily member 4

Research Areas:immunology;Stem cells

Conjugation:

Target Species:Human

Expression Host:HEK293 Cells

Application:

Fusion tag:C-His

UNIProt ID:P23510

Accession:P23510

Background:Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed on the surface of activated B cells,T cells,dendritic cells and endothelial cells. OX40L binds to OX40(CD134),a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional,it has been found association with systemic lupus erythematosus,no association with occurrence of atherosclerosis.

Concentration:

Activity:Not validated for activity

Sequence:Gln51-Leu183

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:14.5 kDa

ObservedMW:30 kDa