Recombinant Human TNFRSF9 Protein(His Tag)

SKU: PDMH100248

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:TNFRSF9

Target Synonym:4 1BB;4 1BB ligand receptor;4-1BB ligand receptor;4-1BB Ligand Receptor T Cell;4-1BB;mouse;homolog of;Antigen 4-1BB Homolog;CD 137;CD137;CD137 antigen;CDw137;HLDA VI;Homolog of mouse 4 1BB;ILA;induced by lymphocyte activation;ILA;Induced by lymphocyte activation;Interleukin activated receptor homolog of mouse Ly63;Ly63;mouse;homolog of;MGC2172;OTTHUMP00000044294;Receptor protein 4 1BB;T cell antigen 4 1BB homolog;T cell antigen ILA;T-cell antigen 4-1BB homolog;T-cell antigen ILA;TNF receptor superfamily member 9;TNFRSF9;TNR9;Tumor necrosis factor receptor superfamily member 9

Research Areas:Cancer;Cell Biology;Immunology;Stem Cells

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-His

UNIProt ID:Q07011

Accession:Q07011

Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Concentration:

Activity:Not validated for activity

Sequence:Val24-Ser186

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:17.8 kDa

ObservedMW:30-35 kDa