Recombinant Human T Beta-4 protein

SKU: CD00857

Size:20 ug

Background:Thymosin Beta 4 is a naturally occurring peptide encoded by the TMSB4X gene located on Chr. X in humans. It is found in high concentrations in blood platelets, wound fluid and other tissues in the body. Tβ-4 is a major actin regulating peptide and the primary function is to stimulate the productions of T cells, which plays important part of the immune system. The thymosin beta-4 peptide, if used after a heart attack, might reactivate cardiac progenitor cells to repair damaged heart tissue.

Research_area:Signal Transduction

Purity:> 97 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Human Thymosin Beta 4

Biological activity:Fully biologically active when compared to standard. The biological activity determined by its ability to produce a protective effect against hydrogen peroxide in primary lung fibroblasts is in a concentration range of .5 - 1 μg/ml.

Synonyms:Tβ-4,FX, PTMB4, TB4X, TMSB4,TMSB4X ,Human

Endotoxin:Less than 1 EU/μg of rHuTβ4 as determined by LAL method.

Storage:-20ºC

Sequence:SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES

uniprot accession:P62328

Molecular weight:Approximately 4.9 kDa, a single non-glycosylated polypeptide chain containing 43 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2 mM PB, pH 7.4.