Size: 200ug. Other sizes are also available. Please Inquire.
In Stock: No
Lead time: 10-20 working days
Research Topic: Signal Transduction
Uniprot ID: P25208
Gene Names: NFYB
Organism: Homo sapiens (Human)
AA Sequence: MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQQIQFS
Expression Region: 1-207aa
Sequence Info: Full Length
Tag Info: N-terminal GST-tagged
MW: 49.8 kDa
Alternative Name(s): CAAT box DNA-binding protein subunit B Nuclear transcription factor Y subunit B
Relevance: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
Reference: "Intron-exon organization of the NF-Y genes. Tissue-specific splicing modifies an activation domain." Li X.-Y., Hooft van Huijsduijnen R., Mantovani R., Benoist C.O., Mathis D. J. Biol. Chem. 267:8984-8990(1992)
Purity: Greater than 90% as determined by SDS-PAGE.
Storage Buffer: Tris-based buffer，50% glycerol
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.