Recombinant Human IL-20RB Protein (Fc Tag)

SKU: PKSH032574

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Cytokines

Abbreviation: IL-20RB

Target Synonym: UNQ;PRO;MGC;DIRS;FNDC;fibronectin type III domain containing;IL-20R;IL20RB;DIRS1;FNDC6;IL-20R2;fibronectin type III domain containing 6;hCG_2022374;IL-20 receptor subunit beta;IL-20RB;IL-20R-beta;interleukin-20 receptor II;Interleukin-20 receptor subunit beta;MGC34923;UNQ557;PRO1114

Research Areas: Cancer;immunology

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-Fc

UNIProt ID: Q6UXL0

Accession: Q6UXL0

Background: Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family

Concentration:

Activity: Not validated for activity

Sequence: Asp30-Ala230

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 49.6 kDa

ObservedMW: 60-85 kDa