Recombinant Human IGFBP2 Protein(His Tag)

SKU: PDMH100239

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:IGFBP2

Target Synonym:BP 2;BP2;IBP 2;IBP-2;IBP2;IBP2;IGF binding protein 2;IGF BP53;IGF-binding protein 2;IGFBP 2;IGFBP-2;IGFBP2;IGFBP53;Insulin like growth factor binding protein 2 36kDa;Insulin like growth factor binding protein 2;Insulin like growth factor-binding protein 2 precursor ;Insulin-like growth factor-binding protein 2

Research Areas:Cancer;Signal transduction

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-His

UNIProt ID:P18065

Accession:P18065

Background:The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with an high affinity, or it can remain intracellular, interacting with an many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.

Concentration:

Activity:Not validated for activity

Sequence:Ala36-Gln325

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:31.7 kDa

ObservedMW:35 kDa