Recombinant Human IFN-Beta1b protein

SKU: CD01600

Size:2 ug

Background:IFN-βs are proteins produced by many cell types including lymphocytes (NK cells, B-cells and T-cells), macrophages, fibroblasts, endothelial cells, osteoblasts and others. They have antiviral activity that it is mainly involved in innate immune response. The IFN-β family has 2 subtypes，which are IFN-β1 (IFNB1) and IFN-β3 (IFNB3) (a gene designated IFN-β2 is actually IL-6). IFN-β1 is used as a treatment for multiple sclerosis as it reduces the relapse rate.

Research_area:Immunology

Purity:> 97 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Interferon-Beta1b, humanIFN-beta1b

Biological activity:Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is no less than 3. × 17 IU/mg.

Synonyms:IFN-β1b,IFB, IFF, IFN-beta, IFNB,IFNB1, Human

Endotoxin:Less than 1 EU/μg of rHuIFN-β1b as determined by LAL method.

Storage:-20ºC

Sequence:MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN

uniprot accession:P1574

Molecular weight:Approximately 2. kDa, a single non-glycosylated polypeptide chain containing 166 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in PBS, pH 7.4, containing 2 % HSA and 3 % mannitol.