Recombinant Human HPGDS/GSTS Protein

SKU: PKSH032528

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: HPGDS;GSTS

Target Synonym: GST Class-Sigma;GSTS;Glutathione S-Transferase;Glutathione-Dependent PGD Synthase;Glutathione-Requiring Prostaglandin D Synthase;H-PGDS;HPGDS;Hematopoietic Prostaglandin D Synthase;PGDS;PTGDS2;Prostaglandin-H2 D-Isomerase

Research Areas: Signal Transduction;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: None

UNIProt ID: O60760

Accession: O60760

Background: Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Leu199

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, pH 7.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 22.3 kDa

ObservedMW: 26 kDa