Recombinant Human GALK1/Galactokinase Protein (His Tag)

SKU: PKSH033673

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: GALK1;Galactokinase

Target Synonym: GALK;GALK1;Galactokinase;Galactose Kinase

Research Areas: Signal Transduction;Cell biology;Cancer;epigenetics and nuclear signal;metabolism;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: C-His

UNIProt ID: P51570

Accession: P51570

Background: Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar molecule called Galactose-1-Phosphate.Thus; a series of additional steps converts Galactose-1-Phosphate to another simple sugar Glucose; which is the main energy source for most cells. Galactokinase deficiency results in Galactosemia II; an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of Galactitol in the lenses.

Concentration:

Activity: Not validated for activity

Sequence: Met1-Leu392

Purity: > 85 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 43.3 kDa

ObservedMW: 45 kDa