Recombinant Human Ephrin-A1/EFNA1 Protein (Fc Tag)

SKU: PKSH032389

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: Ephrin-A1;EFNA1

Target Synonym: EFNA1;EPH-Related Receptor Tyrosine Kinase Ligand 1;EPLG1;Ephrin-A1;Immediate Early Response Protein B61;LERK-1;LERK1;TNF Alpha-Induced Protein 4;TNFAIP4;Tumor Necrosis Factor Alpha-Induced Protein 4

Research Areas: Signal Transduction;Cardiovascular;Neuroscience;

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-Fc

UNIProt ID: P20827

Accession: AAH32698.1

Background: Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.

Concentration:

Activity: Not validated for activity

Sequence: Asp19-Ser182

Purity: > 85 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 46.5 kDa

ObservedMW: 55-60 kDa