Recombinant Human CXCL1 Protein(GST Tag)

SKU: PDEH100462

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:CXCL1

Target Synonym:CXCL;SCYB;Secretory protein N;CINC;NAP;CXCL1;FSP;GRO1;GROa;MGSA;MGSA-a;NAP-3;SCYB1;GRO alpha;CINC-1;C-X-C Motif Chemokine 1;GRO-A;GRO-Alpha(1-73);Growth-Regulated Alpha Protein;GRO-α: MGSAα;Melanoma Growth Stimulatory Activity;NAP3;Neutrophil-Activating Protein 3;Platelet-derived growth factor-inducible protein KC;Secretory protein N51;GRO;alpha;alpha);chemokine (C-X-C motif) ligand 1;Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity;C-X-C motif chemokine ligand 1;Cytokine-induced neutrophil chemoattractant 1;Fibroblast secretory protein;Gro 1;Gro A;GRO protein;Gro1 oncogene;GRO1 oncogene (melanoma growth stimulating activity;GRO1 oncogene (melanoma growth-stimulating activity);GRO-alpha(6-73);homolog of;KC chemokine;melanoma growth stimulatory activity alpha;member 1;MGSA alpha;mouse;N51;Scyb 1;Small inducible cytokine subfamily B

Research Areas:Cancer;Cardiovascular;Neuroscience;Immunology;Signal Transduction;Metabolism

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-GST

UNIProt ID:P09341

Accession:P09341

Background:Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.

Concentration:

Activity:Not validated for activity

Sequence:Ala35-Asn107

Purity:> 85% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method

Calculated MW:43.8 kDa

ObservedMW:38 kDa