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GeneBio Systems

Recombinant Human CASP9 Protein(Sumo Tag)

Recombinant Human CASP9 Protein(Sumo Tag)

PDEH100514

$1,017.00 USD
$1,017.00 USD
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Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:CASP9

Target Synonym:MCH;Apoptotic protease Mch;PPP1R;ICE-LAP;CASP9;APAF-3;APAF3;ICE-LAP6;MCH6;PPP1R56;caspase-9;Caspase 9;CASP-9;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3 (APAF-3);ICE-like apoptotic protease 6 (ICE-LAP6);Apoptosis related cysteine peptidase;Apoptotic protease-activating factor 3;Caspase 9 apoptosis related cysteine peptidase;Caspase 9 Dominant Negative;Caspase 9c;Caspase-9 subunit p10;ICE LAP6;ICE like apoptotic protease 6;ICE-like apoptotic protease 6;protein phosphatase 1;regulatory subunit 56;RNCASP9

Research Areas:

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-Sumo

UNIProt ID:P55211

Accession:P55211

Background:Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

Concentration:

Activity:Not validated for activity

Sequence:Val139-Asp330

Purity:> 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method

Calculated MW:36.4 kDa

ObservedMW:37 kDa

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