Recombinant Human C1QBP Protein (aa 74-282, His Tag)

SKU: PKSH033350

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: C1QBP

Target Synonym: ASF/SF2-Associated Protein p32;C1QBP;C1qBP;Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial;GC1QBP;Glycoprotein gC1qBP;HABP1;Hyaluronan-Binding Protein 1;Mitochondrial Matrix Protein p32;SF2P32;gC1q-R Protein;gC1qR;p33

Research Areas: Microbiology;immunology

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: C-His

UNIProt ID:

Accession: Q07021

Background: Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.

Concentration:

Activity: Not validated for activity

Sequence: Leu74-Gln282

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 20% Glycerol, 1mM DTT, pH 7.5.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 24.9 kDa

ObservedMW: 34 kDa