Recombinant Human ATG4A Protein (His Tag)

SKU: PKSH032099

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: ATG4A

Target Synonym: APG4A;ATG4A;AUT-Like 2 Cysteine Endopeptidase;AUTL2;Autophagin-2;Autophagy-Related Cysteine Endopeptidase 2;Autophagy-Related Protein 4 Homolog A;Cysteine Protease ATG4A;hAPG4A

Research Areas: Signal Transduction;Cell biology;Cardiovascular;Cancer;metabolism;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: Q8WYN0

Accession: Q8WYN0

Background: Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Val398

Purity: > 80 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 47.5 kDa

ObservedMW: 40-55 kDa