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GeneBio Systems

Recombinant HLA-DPA1 Monoclonal Antibody

Recombinant HLA-DPA1 Monoclonal Antibody

SKU:AN301550L

Regular price $424.00 USD
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:HLA-DPA1

Target Synonym:PLT;HLA-DPA;HLA-DPA1;DP(W3);DP(W4);HLA-DP1A;HLADP;HLASB;PLT1;class II;HLA class II histocompatibility antigen DP alpha 1 chain;HLA class II histocompatibility antigen DP alpha chain;HLA DP1A;HLA DPA 1;HLA SB alpha chain;HLADPA1;HLASB histocompatibility type;Human MHC class II HLA SB alpha gene;Major histocompatibility complex class II DP alpha 1;MHC class II antigen;MHC class II DP3 alpha;MHC class II DPA1;MHC class II HLA DPA1 antigen;Primed lymphocyte test 1

Research Areas:Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC;IF

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A249

UNIProt ID:P20036

Accession:

Background:Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous.

Concentration:1 mg/mL

Immunogen:Recombinant human HLA-DPA1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:200-1:1000;IF 1:50

Calculated MW:29 kDa

ObservedMW:33 kDa

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