Recombinant GPNMB Monoclonal Antibody

SKU: AN301540L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:GPNMB

Target Synonym:UNQ;PRO;GPNMB;HGFIN;NMB;Glycoprotein nmb;Glycoprotein nmb like protein;Osteoactivin;Transmembrane glycoprotein;Transmembrane glycoprotein HGFIN;Transmembrane glycoprotein NMB;UNQ1725;PRO9925;Glycoprotein nmb like protein;Gpnmb;HGFIN;NMB;Osteoactivin;Transmembrane glycoprotein;Transmembrane glycoprotein HGFIN;Transmembrane glycoprotein NMB

Research Areas:Immunology;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A239

UNIProt ID:Q14956

Accession:

Background:The protein is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant human GPNMB fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:200-1:1000;FCM 1:50-1:100

Calculated MW:64 kDa

ObservedMW:120,95,65 kDa