Recombinant EIF2S1 Monoclonal Antibody

SKU: AN301512L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:EIF2S1

Target Synonym:EIF2S;EIF;EIF-2;EIF-2A;EIF-2alpha;EIF2;EIF2A;EIF2S1;EIF 2;EIF 2 alpha;EIF 2A;EIF 2alpha;EIF2 alpha;eIF-2-alpha;Eukaryotic translation initiation factor 2 subunit 1;Eukaryotic translation initiation factor 2 subunit 1 alpha;Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa;Eukaryotic translation initiation factor 2 subunit alpha;IF2A

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A211

UNIProt ID:P05198

Accession:

Background:The eukaryotic translation initiation factor 2-α subunit (EIF2S1) is the first regulatory step that catalyzes the initiation of protein synthesis and promotes the binding of the initial tRNA to the 40S ribosomal subunit. As an important translation initiation factor, the eukaryotic initiation factor 2-α subunit is regulated by a variety of signal molecules, that is, it functions by regulating the phosphorylation and acetylation status of EIF2S1. Kinases activated by viral infection (PKR), endoplasmic reticulum stress (PERK/PEK), amino acid deprivation (GCN2) or heme deficiency (HRI) can phosphorylate EIF2S1 to regulate the transcription and translation of cell-related genes and enhance Cell protection mechanism.

Concentration:1 mg/mL

Immunogen:Recombinant human EIF2S1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IHC 1:50-1:100

Calculated MW:36 kDa

ObservedMW:36 kDa