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GeneBio Systems

Recombinant COUP-TFII Monoclonal Antibody

Recombinant COUP-TFII Monoclonal Antibody

AN301980L

$424.00 USD
$424.00 USD
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:COUP-TFII

Target Synonym:SVP;COT;CHTD;NF-E;COUP transcription factor;Apolipoprotein AI regulatory protein;Apolipoprotein A-I regulatory protein;Nuclear receptor subfamily 2 group F member;TFCOUP;COUP TF;COUP-TF;ARP;NR2F2;ARP1;CHTD4;COUPTFB;COUPTFII;NF-E3;SVP40;TFCOUP2;Apolipoprotein AI regulatory protein 1;Apolipoprotein A-I regulatory protein 1;ARP-1;COT2;COUP TF2;COUP transcription factor 2;COUP transcription factor II;COUP-TF II;COUP-TF2;NR2F1;Nuclear receptor subfamily 2 group F member 2

Research Areas:Cardiovascular;Cell Biology;Neuroscience;Epigenetics and Nuclear Signaling;Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;ChIP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A696

UNIProt ID:P24468

Accession:

Background:Chicken ovalbumin upstream promoter transcription factor (COUP-TF) belongs to the NR2 subfamily of the nuclear hormone receptor family. COUP-TFI and COUP-TFII are two of the well-characterized members in the NR2 subfamily. These two members are highly conserved in their two zinc-finger DNA binding domains (DBD) and the ligand binding domain (LBD), and function as repressors or activators of downstream target genes to regulate different biological processes. COUP-TFI and II bind to 5'-AGGTCA-3' motif palindromes, either directly or indirectly, through heterodimer formation with other proteins (e.g. RXRs) to regulate downstream target gene expression. COUP-TFI is involved in neuronal development, tissue patterning, and differentiation. COUP-TFII has been shown to be involved in angiogenesis, glucose homeostasis, and mesenchymal cell commitment.

Concentration:1 mg/mL

Immunogen:Peptide. This information is proprietary to PTMab.

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100;ChIP 6μg/2×106cells

Calculated MW:46 kDa

ObservedMW:46 kDa

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