Recombinant Cofilin Monoclonal Antibody

SKU: AN301117L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Cofilin

Target Synonym:COF;epididymis secretory protein Li;HEL-S;CFL1;CFL;HEL-S-15;cofilin;cofilin-1;18 kDa phosphoprotein;CFL 1;COF1;Cofilin 1;Cofilin 1 non muscle;Cofilin non muscle isoform;epididymis secretory protein Li 15;N-Cofilin;non-muscle isoform;p18;Cofilin

Research Areas:Signal Transduction;Neuroscience;Cancer;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11D14

UNIProt ID:P23528

Accession:

Background:Cofilin 1(CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Cofilin protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:20000-1:50000;WB 1:2000-1:10000

Calculated MW:19 kDa

ObservedMW:19 kDa