Recombinant CD46 Monoclonal Antibody

SKU: AN300250P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:CD46

Target Synonym:MIC;AHUS;TRA2.;AHUS2;MCP;MIC10;TLX;TRA2.10;CD46;CD46 molecule;Membrane Cofactor Protein;Trophoblast Leukocyte Common Antigen

Research Areas:Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC-P;ICC/IF

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:10A2

UNIProt ID:P15529

Accession:

Background:The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Concentration:1 mg/mL

Immunogen:Recombinant Human CD46 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500;ICC/IF 1:20-1:100;

Calculated MW:

ObservedMW: